Incorporation of Trifluoromethylated Proline and Surrogates into Peptides: Application to the Synthesis of Fluorinated Analogues of the Neuroprotective Glycine-Proline-Glutamate (GPE) Tripeptide

Julien Pytkowicz (1) , Gregory Chaume (1) , Nathalie Lensen (1) , Julien Simon , Thierry Brigaud (1)

1 BioCIS - Biomolécules : Conception, Isolement, Synthèse

Domaines: Chimie

Julien Pytkowicz, Gregory Chaume, Nathalie Lensen, Julien Simon, Thierry Brigaud. Incorporation of Trifluoromethylated Proline and Surrogates into Peptides: Application to the Synthesis of Fluorinated Analogues of the Neuroprotective Glycine-Proline-Glutamate (GPE) Tripeptide. Journal of Organic Chemistry, 2016, 13, pp.5381-5392. ⟨10.1021/acs.joc.6b00704⟩. ⟨hal-02980190⟩