Real-Time Imaging of Bacteria/Osteoblast Dynamic Coculture on Bone Implant Material in an in Vitro Postoperative Contamination Model

Victor Prévost , Karine Anselme (1) , Olivier Gallet (2) , Mathilde Hindie (2) , Tatiana Petithory (3) , Jules Valentin (4) , Mathieu Veuillet (3) , Lydie Ploux (5)

1 ICSI - Institut de Chimie des Sufaces et Interfaces
2 ERRMECe - Equipe de recherche sur les relations matrice extracellulaire-cellules
3 IS2M - Institut de Science des Matériaux de Mulhouse
4 LJP - Laboratoire Jean Perrin
5 BB - Biomatériaux et Bioingénierie

Biomedical implants are an important part of evolving modern medicine but have a potential drawback in form of post-operative pathogenic infection. Accordingly, the "race for surface" combat between invasive bacteria and host cells determines the fate of implants. Hence, proper in vitro systems are required to assess effective strategies to avoid infection. In this

Domaines: Ingénierie biomédicale; Matériaux; Microbiologie et Parasitologie

Victor Prévost, Karine Anselme, Olivier Gallet, Mathilde Hindie, Tatiana Petithory, et al.. Real-Time Imaging of Bacteria/Osteoblast Dynamic Coculture on Bone Implant Material in an in Vitro Postoperative Contamination Model. ACS Biomaterials Science and Engineering, 2019, 5 (7), pp.3260-3269. ⟨10.1021/acsbiomaterials.9b00050⟩. ⟨hal-02384099⟩